Training Farmasi, Granulasi dan Kompresi

Alamat Kantor

Jalan Raya Tajem, Dukuh Pokoh Baru, Perum Kampung Asri 2 No B2, RT 2 / RW 19,
Kelurahan Wedomartani, Kec. Ngemplak, Kab. Sleman,
Daerah Istimewa Yogyakarta, 55584. Telp : (0274) 4530527



Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the selection of a particular machine and granulation method, is often done on the basis of tradition, rather than by using strict scientific or cost-benefit criteria. The basic techniques have changed dramatically in recent years and granulation for controlled release, extrusion, spheronisation, fluidization techniques, spray drying, melt extrusion, oral dispersion technology and roller compaction are new technologies that are increasingly being used in modern pharmaceutical production, which exhibit many advantages over previously available techniques. As with granulation, compression is also little understood and why some materials/formulations will compress well whilst others compact with difficulty, is slowly being elucidated. The Course will examine current granulation and compression theory and practice. Emphasis will be made as to how this theory and practice relates to current pharmaceutical development and production, with special reference to the machinery used. Scale-Up, Transfer Technology and SUPAC will also be addressed. A particular feature of the Course will be the workshop on new melt extrusion technology.


The aims of the Course are to provide a comprehensive and sound understanding of the theory and practice of tablet granulation and compression and to appreciate the various processes batch or continuous, that are available. The importance of the granulation process in producing good quality tablets will be emphasized. The modern techniques of extrusion, spheronisation, powder layering, roller compaction, fluid-bed processing, spray drying, melt extrusion, oral dispersion technology and tablet compression will be covered. The Course will be taught primarily by industrial scientists who have been closely involved with investigating these granulation and compression processes and thus a pragmatic approach will be adopted throughout.


At the end of the Course participants will have:

• An understanding of the fundamental principles of granulation and the advantages, disadvantages and potential of the various granulation, layering, spray drying, oral dispersion, extrusion and spheronisation methods

• An understanding of the techniques and processes available for granulation in relation to controlled release products

• Detailed knowledge on current ideas and thoughts on Scale-Up, Transfer Technology and SUPAC

• An appreciation of some of the compression problems that can arise and how they can be overcome

• A knowledge of the factors that should betaken into consideration when selecting granulation and compression equipment


1. Methods and Reasons for Granulating

2. Excipients

3. Properties of Granules

4. Granulation for Controlled Release

5. High Speed Granulation and End-Point Control

6. Integrated Mixer-Granulator Dryers

7. Fluid Bed Granulation

8. Layering

9. Spray Drying

10. Pellet Manufacture

11. Extrusion and Spheronization

12. Hot Melt Extrusion

13. Roller Compaction

14. Compression Theory

15. Compression Machinery

16. Compaction Simulators

17. Tabletting and Tooling Problems

18. Oral Dispersion Tabletting Technology

19. Scale-Up, Transfer Technology and Supac


All who are working in pharmaceutical research, formulation, development, production, QA/QC and registration who require a sound understanding of the various granulation and compression methods and who wish to appreciate some of the advantages of the newer methods of granulation, spheronisation, roller compaction, layering, melt extrusion and compression that are now available.


Ir. Chandra Wahyu Purnomo


Jadwal Berdiklat Training 2020 :

  • 8 sd 9 Januari 2020
  • 22 sd 23 Januari 2020
  • 5 sd 6 Februari 2020
  • 19 sd 20 Februari 2020
  • 4 sd 5 Maret 2020
  • 18 sd 19 Maret 2020
  • 1 sd 2 April 2020
  • 15 sd 16 April 2020
  • 6 sd 7 Mei 2020
  • 20 sd 21 Mei 2020
  • 10 sd 11 Juni 2020
  • 24 sd 25 Juni 2020
  • 9 sd 10 Juli 2020
  • 23 sd 24 Juli 2020
  • 13 sd 14 Agustus 2020
  • 27 sd 28 Agustus 2020
  • 10 sd 11 September 2020
  • 24 sd 25 September 2020
  • 8 sd 9 Oktober 2020
  • 22 sd 23 Oktober 2020
  • 5 sd 6 November 2020
  • 18 sd 19 November 2020
  • 3 sd 4 Desember 2020
  • 17 sd 18 Desember 2020


Investasi dan Lokaspelatihan:

  • Yogyakarta
  • Jakarta
  • Bandung
  • Bali
  • Surabaya
  • Lombok

Catatan : Apabila perusahaan membutuhkan paket in house training, anggaran investasi pelatihan dapat menyesuaikan dengan anggaran perusahaan.

Fasilitas :

  • FREE Airport pickup service (Gratis Antar jemput Hotel/Bandara/Stasiun/Terminal)
  • Module / Handout 
  • Flashdisk
  • Sertifikat 
  • FREE Bag or bagpackers (Tas Training)
  • Training Kit (Dokumentasi photo, Blocknote, ATK, etc)
  • 2xCoffe Break & 1 Lunch, Dinner
  • FREE Souvenir Exclusive
  • Training room full AC and Multimedia